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A cell-permeable, pyrrolidine small molecule that promotes single human embryonic stem cell survival up to 20-fold over background with equal or higher potency than Y-27632.
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Formulation
C14H16N4, HCl
Concentration
2.5 mg/mL
For Use With (Application)
This product is useful for activation of TLR7 and stimulation of TLR7 has been achieved with 5 to 10μL. Use in ligand activation, functional, and in vitro reported in scientific literature (PMID 25957979)
A simple, nonradioactive high throughput-compatible format for assaying the enzyme activity of all sulfotransferases that use 3-phosphoadenosine-5-phosphosulfate (PAPS) as the donor substrate
The NF-κB Activation Inhibitor VII, CID-2858522 controls the biological activity of NF-κB. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.